More on elongation Regulation of Gene Expression Regulation of Globin gene translation by heme
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tRNAs are interpreters of the genetic code Length = 73 – 95 bases Have extensive 2o structure Acceptor arm – position where amino acid attached Anticodon – complementary to mRNA Several covalently modified bases Gray bases are conserved between tRNAs
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Chapter 21 (part 2): Transcriptional regulation and rna processing Processing of Eukaryotic mRNA Splicing of Pre-mRNA
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TFAIIA, TFAIIB – components of RNA polymerase II holo-enzyme complex TFIID – Initiation factor, contains TATA binding protein (TBP) subunit. TATA box recognition. TFIIF – (RAP30/74) decrease affinity to non-promoter DNA
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DNA Polymerase III Subunit Organization DNA Replication is a Processive Process. Stages of DNA Replication
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Ribosomal RNA (rRNA) – integral part of ribosomes (very abundant) Transfer RNA (tRNA) – carries activated amino acids to ribosomes. Messenger RNA (mRNA) – endcodes sequences of amino acids in proteins. Catalytic RNA (Ribozymes) – catalzye cleavage of specific RNA species.
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Hydrophobic interactions – burying hydrophobic purine and pyrimidine rings in interior Stacking interactions – van der Waals interactions between stacked bases. Hydrogen Bonding – H-bonding between bases Charge-Charge Interactions – Electrostatic repulsions of negatively charged phosphate groups are minimized by interaction with cations (e.g. Mg...
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Step 5: Arginase Glucose-Alanine Cycle Catabolism of Carbon Chains From Amino Acids
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Regulation of Bacterial GS by Covalent Modification Glutamate serves as primary N- donor for AA synthesis through transamination reactions Transamination rxns involve Pyridoxol-phosphate and formation of Schiff Base
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100,000 kcal of TAG, 25,000 kcal protein, 600 kcal glycogen, 40 kcal glucose. 24 lbs of body weight is TAG Would need 121lbs of glycogen to store the same amount of energy
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