Sinh học - Chapter 16 (part 2): Fatty acid catabolism (b - Oxidation)
Chapter 16 (part 2): Fatty acid catabolism (b-Oxidation) b-oxidation of odd chain fatty acids b-oxidation of unsaturated fatty acids
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Chapter 16 (Part 2)Fatty acid Catabolism(b-oxidation)Import of acyl-CoA into mitochondriab-oxidationb-oxidationB-oxidation of palmitate (C16:0) yields 106 molecules of ATPC 16:0-CoA + 7 FAD + 7 NAD+ + 7 H20 + 7 CoA 8 acetyl-CoA + 7 FADH2 + 7 NADH + 7 H+2.5 ATPs per NADH = 17.51.5 ATPs per FADH2 = 10.5 10 ATPs per acetyl-CoA = 80Total = 108 ATPs2 ATP equivalents (ATP AMP + PPi, PPi 2 Pi) consumed during activation of palmitate to acyl-CoANet yield = 106 ATPsAcyl-CoA DehydrogenaseXb-oxidation of odd chain fatty acidsb-oxidation of unsaturated fatty acidsb-oxidation of fatty acids with even numbered double bondsFormation of ketone bodiesRe-utilization of ketone bodies
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